Publications

1999Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain↗2,542 2000Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome↗1,770

1998Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin↗Nature medicine888 2024Identification of direct connections between the dura and the brain↗Nature274 2016Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures↗Nature protocols138 2020Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway↗Nature communications42 2025A route for cerebrospinal fluid flow through leptomeningeal arterial–venous overlaps enables macromolecule and fluid shunting↗Nature neuroscience23

2003Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits↗2,595 2007Diffusion tensor imaging reliably detects experimental traumatic axonal injury and indicates approximate time of injury↗529 2020Zika virus infection in the developing mouse produces dramatically different neuropathology dependent on viral strain↗25 2003DEVELOPMENT/PLASTICITY/REPAIR-Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits↗

2002Antiepileptic drugs and apoptotic neurodegeneration in the developing brain↗1,008

2013Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration↗604 2013Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration↗14

2002Ethanol-induced caspase-3 activation in the in vivo developing mouse brain↗282 2001Apoptosis in the in vivo mammalian forebrain↗223 2005Role of caspase-3 in ethanol-induced developmental neurodegeneration↗139 1998Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease↗120 2001Joann Labruyere,* YQ Qin,* Chrysanthy Ikonomidou, and John W. Olney↗

2026Post-hemorrhagic hydrocephalus of prematurity is associated with disruption of tight junctions and increased macrophage activity in the choroid plexus↗Fluids and Barriers of the CNS1 2024Trackins (Trk-targeting drugs): a novel therapy for different diseases↗Pharmaceuticals13 2021nNOS regulates ciliated cell polarity, ciliary beat frequency, and directional flow in mouse trachea↗Life science alliance17 2019Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopment↗Neurobiology of learning and memory 165, 10683432 2019Modeling traumatic brain injury: mechanisms of early neuronal and axon degeneration in the infant rodent brain↗Biomedical Reviews 30, 25-361 2018A gyral coordinate system predictive of fibre orientations↗Neuroimage 176, 417-43021 2017Improved tractography using asymmetric fibre orientation distributions↗Neuroimage 158, 205-21860 2016Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts↗The FASEB journal36 2016Fibers crossing the white/gray matter boundary: a semi-global, histology-informed dMRI model↗Annual Meeting of the International Society for Magnetic Resonance in …5 2016Improved tractography by modelling sub-voxel fibre patterns using asymmetric fibre orientation distributions↗Proc. Int. Soc. Magn. Reson. Med. Presented at the ISMRM. ISMRM5 2015Experimental subarachnoid haemorrhage results in multifocal axonal injury↗Brain59 2015A generative model of white matter axonal orientations near the cortex↗Proceedings of the ISMRM Meeting 3516 2015The amazing brain↗6 2014Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain↗Anesthesiology261 2014Mapping connections in humans and non-human primates: aspirations and challenges for diffusion imaging↗Diffusion mri, 337-358162 2014The Ultrastructural Identity of Alzheimer's Pathology: Lessons from Animal Models↗Journal of neurological disorders1 2013Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain↗British journal of anaesthesia453 2013Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain↗Acta neuropathologica communications108 2013Comparison of diffusion MRI predictions and histology in the macaque brain↗Proceedings of the International Society for Magnetic Resonance in Medicine …14 2013SOS for SOC: the renaissance of a seemingly ubiquitous organelle↗Biomedical Reviews 24, 9-101 2013nGf-PC-Ad ConneCtion↗Adipobiology 5, 19-221 2013PROPOFOL-INDUCED APOPTOSIS OF NEURONS AND OLIGODENDROCYTES IN THE FETAL RHESUS MACAQUE BRAIN↗Anesthesia And Analgesia 116, 160-160 2012Isoflurane‐induced apoptosis of oligodendrocytes in the neonatal primate brain↗Annals of neurology327 2012Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer’s disease↗International journal of clinical and experimental pathology26 2012Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain↗Proceedings of the American Society of Anesthesiologists, Washington, DC …5 2012Electron microscopist's view of the Alzheimer's plaque↗Biomedical Reviews 23, 9-174 2011Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivity↗Journal of Neuropathology & Experimental Neurology393 2011Diffusion characteristics associated with neuronal injury and glial activation following hypoxia‐ischemia in the immature brain↗Magnetic resonance in medicine46 2010Axons pull on the brain, but tension does not drive cortical folding↗335 2010A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death↗The American journal of pathology21 2008Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons↗Experimental neurology118 2007Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injury↗Experimental neurology385 2006Spatiotemporal evolution of apoptotic neurodegeneration following traumatic injury to the developing rat brain↗Brain research43 2006Ultrastructural characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced cell death in embryonic dopaminergic neurons↗Apoptosis20 2006Does Traumatic Brain Injury Trigger Delayed Neuronal Death through Apoptosis?↗Academic Emergency Medicine1 2006366: Histologic Assessment of Free Radical Injury and Apoptotic Cell Death After Severe Traumatic Brain Injury↗Annals of Emergency Medicine 2006Characterization of white matter degeneration following mild traumatic brain injury to the infant P7 mouse↗Journal Of Neurotrauma 2005Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures↗Developmental Brain Research207 2005Histological characterization of graded traumatic brain injury in the P7 mouse↗Journal Of Neurotrauma 2005Apoptosis Is Present in Severe but Not Mild Traumatic Brain Injury↗Academic Emergency Medicine 2004Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia↗Current Molecular Medicine99 2003Ethanol-induced apoptosis in the developing visual system during synaptogenesis↗Investigative Ophthalmology & Visual Science106 2003Nuclear translocation of nuclear transcription factor-κB by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in …↗Molecular pharmacology51 2003Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA receptors in several brain regions↗Brain research30 2002Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain↗Developmental Brain Research374 2002Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity↗Molecular psychiatry168 2002Apoptosis in the mammalian nervous system: developmental and clinical implications↗Biomedical Reviews 13, 49-61 2001Neurotransmitters and apoptosis in the developing brain↗Biochemical pharmacology395 2000Rapid and ion-independent neuronal pathology induced by kainate in adult rat retina ex vivo.↗Investigative Ophthalmology & Visual Science 1999Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain↗Journal of Comparative Neurology279 1999Expression of nitric oxide synthase isoforms (NOS II and NOS III) in adult rat lung in hyperoxic pulmonary hypertension↗Cell and tissue research48 1998Modeling pediatric head trauma: mechanisms of degeneration and potential strategies for neuroprotection↗Restorative neurology and neuroscience35 1997Ultrastructural organization of elastic fibers in umbilical vessels↗European Journal Of Morphology 1997Intermediate cytoskeletal proteins in placental and umbilical cord vessels↗European Journal Of Morphology 1996Radioimmunological and immunohistochemical study of carcinoembryonic antigen in pleomorphic adenoma and mucoepidermoid carcinoma of the salivary glands.↗General & diagnostic pathology20 1996Immunomorphological characteristics of pleomorphic adenoma of salivary glands↗Bulletin du GIRSO11 1996Expression of cytoskeletal proteins and ATPase activity in bovine femoral artery and vein intima↗Murcia: F. Hernández3 1995Long-term sensory denervation does not modify endothelial function or endothelial substance P and nitric oxide synthase in rat mesenteric arteries↗Journal of vascular research10 1995Ultrastructural localisation of nitric oxide synthase in vascular endothelial cells↗European Journal of Morphology 1994Nitric oxide synthase (NOS) in the human umbilical cord vessels. An immunohistochemical study↗Acta histochemica24 1994Localisation of nitric oxide synthase and its colocalisation with vasoactive peptides in coronary and femoral arteries. An electron microscope study↗Journal of anatomy20 1994Increase in immunoreactivity to endothelin-1 in the mucosal vasculature and epithelium of the large intestine during chronic hypoxia↗Journal of Anatomy18 1993Colocalization of vasoactive substances in the endothelial cells of human umbilical vessels↗Cell and tissue research33 1993Intermediate filaments and ATPase activity in the vascular wall of vertebrates↗Acta histochemica3 1993ULTRASTRUCTURE OF THE WALL OF THE TERMINAL VESSELS OF THE STOMACH MUCOSA↗Scripta Scientifica Medica 28, 11-16 1992Endothelium-derived biologically active substance: von Willebrand factor and endothelin↗Biomedical Reviews 1, 39-45 1991Effect of vasoactive amines on Weibel-Palade bodies in capillary endothelial cells↗Experientia17 1991Distribution of anionic sites in gut tissue: an electron-microscopical study↗Cell and tissue research2 1989ULTRASTRUCTURAL-CHANGES IN COLON MICROVASCULAR ENDOTHELIAL-CELLS AFTER RESERPINE TREATMENT↗Dokladi Na Bolgarskata Akademiya Na Naukite 1989Teltsa na Vaǐbel-Palade i faktor na fon vilebrand v endotelnata kletka.↗Eksperimentalna Medicina i Morfologiya 1989Weibel-Palade bodies and von Willebrand factor in endothelial cells↗Eksperimentalna Meditsina i Morfologiia 1988ULTRASTRUCTURE OF MUCOSAL TERMINAL VESSELS IN THE COLON OF SPONTANEOUSLY HYPERTENSIVE RATS↗Dokladi Na Bolgarskata Akademiya Na Naukite 1987Effect of histamine on the ultrastructure of mucosal circulatory vessels in rat large intestine.↗Acta Morphologica Hungarica1 1986ULTRASTRUCTURE OF THE WALL OF TERMINAL MUCOSAL VESSELS OF THE GASTROINTESTINAL-TRACT-EFFECT OF SEROTONIN↗Dokladi Na Bolgarskata Akademiya Na Naukite —Department of Neuroscience↗1 —available at www. sciencedirect. com↗infrared spectroscopy 1107, 206, 0