Publications

1999Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain2,542 2000Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome1,770

1998Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxinNature medicine888 2024Identification of direct connections between the dura and the brainNature274 2016Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron culturesNature protocols138 2020Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathwayNature communications42 2025A route for cerebrospinal fluid flow through leptomeningeal arterial–venous overlaps enables macromolecule and fluid shuntingNature neuroscience23

2003Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits2,595 2007Diffusion tensor imaging reliably detects experimental traumatic axonal injury and indicates approximate time of injury529 2020Zika virus infection in the developing mouse produces dramatically different neuropathology dependent on viral strain25 2003DEVELOPMENT/PLASTICITY/REPAIR-Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

2002Antiepileptic drugs and apoptotic neurodegeneration in the developing brain1,008

2013Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration604 2013Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration14

2002Ethanol-induced caspase-3 activation in the in vivo developing mouse brain282 2001Apoptosis in the in vivo mammalian forebrain223 2005Role of caspase-3 in ethanol-induced developmental neurodegeneration139 1998Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease120 2001Joann Labruyere,* YQ Qin,* Chrysanthy Ikonomidou, and John W. Olney

2026Post-hemorrhagic hydrocephalus of prematurity is associated with disruption of tight junctions and increased macrophage activity in the choroid plexusFluids and Barriers of the CNS1 2024Trackins (Trk-targeting drugs): a novel therapy for different diseasesPharmaceuticals13 2021nNOS regulates ciliated cell polarity, ciliary beat frequency, and directional flow in mouse tracheaLife science alliance17 2019Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopmentNeurobiology of learning and memory 165, 10683432 2019Modeling traumatic brain injury: mechanisms of early neuronal and axon degeneration in the infant rodent brainBiomedical Reviews 30, 25-361 2018A gyral coordinate system predictive of fibre orientationsNeuroimage 176, 417-43021 2017Improved tractography using asymmetric fibre orientation distributionsNeuroimage 158, 205-21860 2016Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human heartsThe FASEB journal36 2016Fibers crossing the white/gray matter boundary: a semi-global, histology-informed dMRI modelAnnual Meeting of the International Society for Magnetic Resonance in …5 2016Improved tractography by modelling sub-voxel fibre patterns using asymmetric fibre orientation distributionsProc. Int. Soc. Magn. Reson. Med. Presented at the ISMRM. ISMRM5 2015Experimental subarachnoid haemorrhage results in multifocal axonal injuryBrain59 2015A generative model of white matter axonal orientations near the cortexProceedings of the ISMRM Meeting 3516 2015The amazing brain6 2014Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brainAnesthesiology261 2014Mapping connections in humans and non-human primates: aspirations and challenges for diffusion imagingDiffusion mri, 337-358162 2014The Ultrastructural Identity of Alzheimer's Pathology: Lessons from Animal ModelsJournal of neurological disorders1 2013Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brainBritish journal of anaesthesia453 2013Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brainActa neuropathologica communications108 2013Comparison of diffusion MRI predictions and histology in the macaque brainProceedings of the International Society for Magnetic Resonance in Medicine …14 2013SOS for SOC: the renaissance of a seemingly ubiquitous organelleBiomedical Reviews 24, 9-101 2013nGf-PC-Ad ConneCtionAdipobiology 5, 19-221 2013PROPOFOL-INDUCED APOPTOSIS OF NEURONS AND OLIGODENDROCYTES IN THE FETAL RHESUS MACAQUE BRAINAnesthesia And Analgesia 116, 160-160 2012Isoflurane‐induced apoptosis of oligodendrocytes in the neonatal primate brainAnnals of neurology327 2012Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer’s diseaseInternational journal of clinical and experimental pathology26 2012Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brainProceedings of the American Society of Anesthesiologists, Washington, DC …5 2012Electron microscopist's view of the Alzheimer's plaqueBiomedical Reviews 23, 9-174 2011Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivityJournal of Neuropathology & Experimental Neurology393 2011Diffusion characteristics associated with neuronal injury and glial activation following hypoxia‐ischemia in the immature brainMagnetic resonance in medicine46 2010Axons pull on the brain, but tension does not drive cortical folding335 2010A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal deathThe American journal of pathology21 2008Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neuronsExperimental neurology118 2007Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injuryExperimental neurology385 2006Spatiotemporal evolution of apoptotic neurodegeneration following traumatic injury to the developing rat brainBrain research43 2006Ultrastructural characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced cell death in embryonic dopaminergic neuronsApoptosis20 2006Does Traumatic Brain Injury Trigger Delayed Neuronal Death through Apoptosis?Academic Emergency Medicine1 2006366: Histologic Assessment of Free Radical Injury and Apoptotic Cell Death After Severe Traumatic Brain InjuryAnnals of Emergency Medicine 2006Characterization of white matter degeneration following mild traumatic brain injury to the infant P7 mouseJournal Of Neurotrauma 2005Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structuresDevelopmental Brain Research207 2005Histological characterization of graded traumatic brain injury in the P7 mouseJournal Of Neurotrauma 2005Apoptosis Is Present in Severe but Not Mild Traumatic Brain InjuryAcademic Emergency Medicine 2004Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemiaCurrent Molecular Medicine99 2003Ethanol-induced apoptosis in the developing visual system during synaptogenesisInvestigative Ophthalmology & Visual Science106 2003Nuclear translocation of nuclear transcription factor-κB by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in …Molecular pharmacology51 2003Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA receptors in several brain regionsBrain research30 2002Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brainDevelopmental Brain Research374 2002Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicityMolecular psychiatry168 2002Apoptosis in the mammalian nervous system: developmental and clinical implicationsBiomedical Reviews 13, 49-61 2001Neurotransmitters and apoptosis in the developing brainBiochemical pharmacology395 2000Rapid and ion-independent neuronal pathology induced by kainate in adult rat retina ex vivo.Investigative Ophthalmology & Visual Science 1999Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brainJournal of Comparative Neurology279 1999Expression of nitric oxide synthase isoforms (NOS II and NOS III) in adult rat lung in hyperoxic pulmonary hypertensionCell and tissue research48 1998Modeling pediatric head trauma: mechanisms of degeneration and potential strategies for neuroprotectionRestorative neurology and neuroscience35 1997Ultrastructural organization of elastic fibers in umbilical vesselsEuropean Journal Of Morphology 1997Intermediate cytoskeletal proteins in placental and umbilical cord vesselsEuropean Journal Of Morphology 1996Radioimmunological and immunohistochemical study of carcinoembryonic antigen in pleomorphic adenoma and mucoepidermoid carcinoma of the salivary glands.General & diagnostic pathology20 1996Immunomorphological characteristics of pleomorphic adenoma of salivary glandsBulletin du GIRSO11 1996Expression of cytoskeletal proteins and ATPase activity in bovine femoral artery and vein intimaMurcia: F. Hernández3 1995Long-term sensory denervation does not modify endothelial function or endothelial substance P and nitric oxide synthase in rat mesenteric arteriesJournal of vascular research10 1995Ultrastructural localisation of nitric oxide synthase in vascular endothelial cellsEuropean Journal of Morphology 1994Nitric oxide synthase (NOS) in the human umbilical cord vessels. An immunohistochemical studyActa histochemica24 1994Localisation of nitric oxide synthase and its colocalisation with vasoactive peptides in coronary and femoral arteries. An electron microscope studyJournal of anatomy20 1994Increase in immunoreactivity to endothelin-1 in the mucosal vasculature and epithelium of the large intestine during chronic hypoxiaJournal of Anatomy18 1993Colocalization of vasoactive substances in the endothelial cells of human umbilical vesselsCell and tissue research33 1993Intermediate filaments and ATPase activity in the vascular wall of vertebratesActa histochemica3 1993ULTRASTRUCTURE OF THE WALL OF THE TERMINAL VESSELS OF THE STOMACH MUCOSAScripta Scientifica Medica 28, 11-16 1992Endothelium-derived biologically active substance: von Willebrand factor and endothelinBiomedical Reviews 1, 39-45 1991Effect of vasoactive amines on Weibel-Palade bodies in capillary endothelial cellsExperientia17 1991Distribution of anionic sites in gut tissue: an electron-microscopical studyCell and tissue research2 1989ULTRASTRUCTURAL-CHANGES IN COLON MICROVASCULAR ENDOTHELIAL-CELLS AFTER RESERPINE TREATMENTDokladi Na Bolgarskata Akademiya Na Naukite 1989Teltsa na Vaǐbel-Palade i faktor na fon vilebrand v endotelnata kletka.Eksperimentalna Medicina i Morfologiya 1989Weibel-Palade bodies and von Willebrand factor in endothelial cellsEksperimentalna Meditsina i Morfologiia 1988ULTRASTRUCTURE OF MUCOSAL TERMINAL VESSELS IN THE COLON OF SPONTANEOUSLY HYPERTENSIVE RATSDokladi Na Bolgarskata Akademiya Na Naukite 1987Effect of histamine on the ultrastructure of mucosal circulatory vessels in rat large intestine.Acta Morphologica Hungarica1 1986ULTRASTRUCTURE OF THE WALL OF TERMINAL MUCOSAL VESSELS OF THE GASTROINTESTINAL-TRACT-EFFECT OF SEROTONINDokladi Na Bolgarskata Akademiya Na Naukite n.d.Department of Neuroscience1 n.d.available at www. sciencedirect. cominfrared spectroscopy 1107, 206, 0